Broncos at Giants

The Manning brothers will face off for the third and possibly last time. Peyton’s Colts trumped Eli’s Giants both times, and as much as it pains me to say this as a Giants fan, I think Peyton will come out on top a third time.

Both of these teams boast championship caliber quarterbacks and a stable of highly skilled wide receivers, so this should be a high scoring affair. The Giant’s secondary players and linebackers are their weakness this year.

Peyton should pick apart the Giants defense easily unless they can get pressure from their once unstoppable pass rush including Jason Pierre Paul and Justin Tuck.

The Giants offense should be a strong suit with Hakeem Nicks, Victor Cruz, Rueben Randle and David Wilson. I think that Hakeem Nicks is the X factor. If he is healthy, the Giants are a completely different team. This will free up Cruz even more in the slot and will avoid double teams. The Giants offense will be strong, but their defense will be their downfall against the Broncos.

The Pick

Denver: Colin, Stu, Rory and Julia

New York: Taylor, Owen

49ers at Seahawks

This matchup features possibly the two best teams in the NFC. Two of the most talented teams on offense and defense, they both feature young talented quarterbacks with tremendous passing and running abilities.

The 49ers just may be the best team in football. The Seahawks have an incredible home field advantage. No matter how loud that stadium is though, I think the 49ers will win.

Colin Kaepernick, Frank Gore, Vernon Davis and Anquan Boldin combine for an explosive offense to go along with one of the best defenses in the NFL.

Kaepernick has sensational talent, as does Russell Wilson. Kaepernick nearly won the Super Bowl in not even his first full season as a starter.

The defense and running game of these teams is about evenly matched so I think the 49ers win an extremely tough and entertaining game with their passing game.

The Picks

San Fransisco: Colin, Taylor, Owen, Jake, Stu, Rory and Julia

Seattle: Jake

Steelers at Bengals

This matchup features a Steelers team with championship experience, but that has fallen in the rankings from one of the top teams to a middle of the road team.

Ben Roethlisberger has to cope with a weak and inexperienced offensive line against a stout Bengals defense.

As HBO’s featured team on “Hard Knocks,” the Bengals are

an up-and-coming team with potential to do some serious damage in a currently weak AFC.

Defense will be the key for the Steelers this season as Troy Polamalu and Lamarr Woodley enter the 2013 season healthy.

Two-time champion Roethlisberger will have to adjust to his new offense after the departure of Mike Wallace. Mike Tomlin will maximize the talent of the Steelers this year, but it wont be enough against this emerging powerhouse in Cincinnati.

The Picks

Pittsburgh: Julia

Cincinnati: Colin, Taylor, Owen, Jake, Stu, Rory

Vikings at Bears

Adrian Peterson essentially coaxed the Minnesota Vikings to the playoffs last year by himself.

Greg Jennings and Cordarelle Patterson are nice additions, but Christian Ponder is still too poor 12